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Proc Natl Acad Sci U S A ; 117(29): 16732-16738, 2020 07 21.
Article in English | MEDLINE | ID: covidwho-629461

ABSTRACT

The coronavirus disease 2019 (COVID-19) pandemic has placed epidemic modeling at the forefront of worldwide public policy making. Nonetheless, modeling and forecasting the spread of COVID-19 remains a challenge. Here, we detail three regional-scale models for forecasting and assessing the course of the pandemic. This work demonstrates the utility of parsimonious models for early-time data and provides an accessible framework for generating policy-relevant insights into its course. We show how these models can be connected to each other and to time series data for a particular region. Capable of measuring and forecasting the impacts of social distancing, these models highlight the dangers of relaxing nonpharmaceutical public health interventions in the absence of a vaccine or antiviral therapies.


Subject(s)
Betacoronavirus/pathogenicity , Coronavirus Infections/prevention & control , Coronavirus Infections/transmission , Infection Control/methods , Infection Control/organization & administration , Models, Theoretical , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Pneumonia, Viral/transmission , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/virology , Humans , Pneumonia, Viral/epidemiology , Pneumonia, Viral/virology , Public Health , SARS-CoV-2 , United States/epidemiology
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